Professor
Fields of Interest
Biography
The Leaché Lab at the University of Washington in Seattle, jointly housed in the Department of Biology and the Burke Museum of Natural History and Culture, is led by Professor Adam Leaché. The lab investigates the evolutionary biology, systematics, and biodiversity of reptiles and amphibians, integrating extensive fieldwork, museum-based research, and modern genomic approaches. Research in the lab focuses on understanding how species form, how they are related, and how their histories can be reconstructed using genomic data. Much of the lab’s work centers on phylogenetics and systematics, with an emphasis on developing and applying methods to infer evolutionary relationships and assess species boundaries. This includes studies of phylogeography and species delimitation, where the lab explores how geography, genetics, and historical processes shape the structure and divergence of populations. The team frequently develops and tests analytical and computational tools through computer simulations and bioinformatics pipelines to improve the reliability of evolutionary inferences from genetic datasets. A defining feature of the lab is its integration of field research with the herpetology and genetic resources collections of the Burke Museum. Connecting living populations with historical specimens allows the lab to examine biodiversity across both space and time, providing robust insights into lineage diversification and evolutionary processes. The lab’s work has contributed significantly to understanding species boundaries and evolutionary histories in numerous herpetological groups, with implications for both taxonomy and conservation. Interesting in joining? Undergraduate students should send an introductory email to inquire about current openings. Graduate students should send an introductory email that includes the following: 1) a brief overview of your background and research experience, 2) a curriculum vitae, 3) copies of any relevant publications, and 4) a description of your Ph.D. research goals.
Dr. Leaché is a Professor of Biology at the University of Washington and Curator of Herpetology and Genetic Resources at the Burke Museum of Natural History and Culture. He received his Ph.D. from the University of California, Berkeley. He is a former McNair Scholar, recipient of the UW Distinguished Teaching Award, and a Fulbright Scholar. He is also a National Institutes of Health Genome Training Grant Faculty Member through the Genome Sciences Department.
Academic History
• NSF Bioinformatics Postdoc., UC Davis, 2008–2010
• Ph.D., Integrative Biology, UC Berkeley, 2008
• M.S., Biology, San Diego State University, 2000
• B.S., Biology, San Diego State University, 1997
• A.A., Orange Coast College, Costa Mesa, CA, 1995
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Selected Research
- The spectre of too many species, Leaché Adam D, Rannala Bruce, Yang Ziheng, and Zhu Tianqi, Systematic Biology, Volume 68, p.168–181 (2019)
- A genomic evaluation of taxonomic trends through time in coast horned lizards (genus \textitPhrynosoma), Leaché Adam D, McElroy Matthew T, and Trinh Anna, Molecular Ecology, Volume 27, p.2884–2895 (2018)
- The utility of single nucleotide polymorphism (SNP) data in phylogenetics, Leaché Adam D and Oaks Jamie R, Annual Review of Ecology, Evolution, and Systematics, Volume 48, p.69–84 (2017)
- Bayesian inference of species diffusion in the West African Agama agama species group (Reptilia, Agamidae), Leaché Adam D, Fujita Matthew K, others, Grummer Jared A, Miller Michael, Krishnan Sneha, Böhme Wolfgang, Schmitz Andreas, Lebreton Matthew, Ineich Ivan, and Chirio Laurent, Systematics and Biodiversity, p.1–12 (2016)
- Survey for Batrachochytrium dendrobatidis in North Cascades National Park, Washington, USA, Grummer Jared A. and Leaché Adam D., Herpetological Review, 09/2016, Volume 47, Issue 3 (2016)
- Phylogenomics of phrynosomatid lizards: conflicting signals from sequence capture versus restriction site associated DNA sequencing, Leaché Adam D, Linkem Charles W, Grummer Jared A, Chavez Andreas S, Jones Leonard N, and Gottscho Andrew D, Genome biology and evolution, Volume 7, p.706–719 (2015)
- Estimating the temporal and spatial extent of gene flow among sympatric lizard populations (genus Sceloporus) in the southern Mexican highlands, Leaché Adam D, de Oca Adrián Nieto-Mont, Grummer Jared A, Calderón-Espinosa Martha L, Smith Eric N, and de la Cruz Fausto R Méndez-, Molecular ecology, Volume 24, p.1523–1542 (2015)
- Short tree, long tree, right tree, wrong tree: new acquisition bias corrections for inferring SNP phylogenies, Leaché Adam D, Banbury Barbara L, Felsenstein Joseph, de Oca Adrián Nieto-Mont, and Stamatakis Alexandros, Systematic Biology, Volume 64, p.1032–1047 (2015)
- Species Delimitation using Genome-Wide SNP Data., Leaché Adam D, Fujita Matthew K, Minin Vladimir N, and Bouckaert Remco R, Systematic biology, 2014 Mar 12 (2014)
- A new species of horned lizard (genus \textit{Phrynosoma} from Guerrero, Mexico, with an updated multilocus phylogeny, Leaché A D, Nieto-Montes de Oca A, Arenas-Moreno D, and Beltrán-Sanchez E, Herpetologica, Volume 70, Number 2, p.in press (2014)
- Species Delimitation using Genome-Wide SNP Data, Leaché Adam D, Fujita Matthew K, Minin Vladimir N, and Bouckaert Remco R, Systematic Biology, Oxford University Press (2014)
- The influence of gene flow on species tree estimation: a simulation study, Harris Rebecca B, Leaché Adam D, Rannala Bruce, and Yang Ziheng, Systematic biology, Volume 63, Number 1, p.17–30, Oxford University Press (2014)
- Phylogeography of the Trans-Volcanic bunchgrass lizard (Sceloporus bicanthalis) across the highlands of south-eastern Mexico, Leaché Adam D, Palacios Julia A, Minin Vladimir N, and Bryson Robert W, Biological Journal of the Linnean Society, Volume 110, Number 4, p.852–865, Wiley Online Library (2013)
- Comparative Species Divergence across Eight Triplets of Spiny Lizards (Sceloporus) Using Genomic Sequence Data, Maliska Max E, Harris Rebecca B, Leaché Adam D, and Linkem Charles W, Genome biology and evolution, Volume 5, Number 12, p.2410–2419, Oxford University Press (2013)
- Additions to the lizard diversity of the Horn of Africa: Two new species in the Agama spinosa group, Wagner Philipp, Leache Adam, Mazuch Tomáš, and Boehme Wolfgang, Amphibia–Reptilia, Volume 34, p.363–387 (2013)
- Phylogeography of the Trans-Volcanic bunchgrass lizard (Sceloporus bicanthalis) across the highlands of south-eastern Mexico, Leaché Adam D, Palacios Julia A, Minin Vladimir N, and Bryson Robert W, Biological Journal of the Linnean Society, Volume 110, Number 4, p.852–865 (2013)
- Molecular Identification of A Hitchhiking Frog, Leaché Adam D and Sherman Erica M, Northwestern Naturalist, Volume 94, Number 1, p.81–84, Society for Northwestern Vertebrate Biology Department of Psychology, Indiana University, Bloomington, Indiana 47405 (2013)
- The accuracy of species tree estimation under simulation: a comparison of methods., Leaché Adam D and Rannala Bruce, Systematic biology, 2011 Mar, Volume 60, Issue 2, p.126-37 (2011)
- Bayesian species delimitation in West African forest geckos (Hemidactylus fasciatus)., Leaché Adam D and Fujita Matthew K, Proceedings. Biological sciences / The Royal Society, 2010 Oct 22, Volume 277, Issue 1697, p.3071-7 (2010)
- Species tree discordance traces to phylogeographic clade boundaries in North American fence lizards (Sceloporus)., Leaché Adam D, Systematic biology, 2009 Dec, Volume 58, Issue 6, p.547-59 (2009)
- Chromosome evolution and diversification in North American spiny lizards (genus Sceloporus)., Leaché A D and Sites J W, Cytogenetic and genome research, 2009, Volume 127, Issue 2-4, p.166-81 (2009)
- Hybridization between multiple fence lizard lineages in an ecotone: locally discordant variation in mitochondrial DNA, chromosomes, and morphology, Leache A D and Cole C J, 2007, Volume 16, Issue 5, p. - -1054 (2007)
- Phylogenetic relationships of horned lizards (Phrynosoma) based on nuclear and mitochondrial data: Evidence for a misleading mitochondrial gene tree, Leache A D and McGuire J A, 2006, Volume 39, Issue 3, p. - -644 (2006)
- Molecular systematics of the Eastern Fence Lizard (Sceloporus undulatus): A comparison of parsimony, likelihood, and Bayesian approaches, Leache A D and Reeder T W, 2002, Volume 51, Issue 1, p. - -68 (2002)
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