Professor Emeritus
Fields of Interest
Biography
My research involves the integration between mechanism and function in animal behavior, with an emphasis on acoustic communication in birds and frogs. The principal current focus is on the song control system in the brains of songbirds. I emphasize a comparative, evolutionary approach to this system, and combine behavioral studies in the field with laboratory techniques in neuroendocrinology, neuroanatomy, molecular biology, and signal analysis. I am currently pursuing three major topics of study in the song system. One concerns the physiological and molecular mechanisms, and the behavioral consequences, of seasonal plasticity observed in the morphology of song regions of the brain. A second topic concerns the recruitment of new neurons to a song nucleus in the forebrain of adult birds, studied from the perspective of its physiological regulation and the influence of environmental factors. The third topic relates to the observation that neurons in song control nuclei receive input from auditory regions, and respond selectively to the presentation of conspecific song. I am investigating the role of song nuclei in the behavioral recognition of conspecific song in the contexts of mate choice and territorial defense.
Eliot Brenowitz received his Ph.D. in 1982 from Cornell University, where his dissertation was on environmental influences on song communication in red-winged blackbirds. He did postdoctoral research at UCLA in the laboratory of Arthur Arnold, looking at the neuroendocrine basis of song duetting behavior in several species of tropical birds. Brenowitz joined the faculty at UW in 1987 and holds appointments as professor in the departments of Biology and Psychology and the Graduate Program in Neurobiology and Behavior. He is also a member of the Virginia Merrill Bloedel Hearing Research Center. Brenowitz has served as an Alfred P. Sloan Research Fellow and a Bloedel Hearing Research Scholar. He is a Fellow of the American Association for the Advancement of Science and of the Animal Behavior Society, and a recipient of a Research Scientist Development Award from the National Institutes of Health.
-
Selected Research
- Language and birdsong: Introduction to the special issue, Brenowitz E A, Perkel D J, and Osterhout L, Brain Lang (9999)
- It takes a seasoned bird to be a good listener: communication between the sexes, Brenowitz Eliot A and Remage-Healey Luke (2016)
- Adult Neurogenesis Leads to the Functional Reconstruction of a Telencephalic Neural Circuit, Brenowitz E A, Cohen R. E., Macedo-Lima M., and Miller K. E. (2016)
- Emerging from the bottleneck: benefits of the comparative approach to modern neuroscience, Brenowitz Eliot A and Zakon Harold H. (2015)
- Seasonal Plasticity of Precise Spike Timing in the Avian Auditory System, Brenowitz Eliot A, Rubel Edwin W, Caras Melissa L., and Sen Kamal (2015)
- Reactive Neurogenesis in Response to Naturally Occurring Apoptosis in an Adult Brain, Brenowitz E A, Larson T A, Thatra N M, and Lee B H, The Journal of Neuroscience, 9/2014, Volume 34, Issue 39 (2014)
- Postsynaptic neural activity regulates neuronal addition in the adult avian song control system, Brenowitz E A, Perkel D J, Gale S D, Larson Tracy A, Thatra N M, Caras M L, Wang TW, and Miller KE, PNAS, 10/2013, Volume 110, Issue 41 (2013)
- Post-synaptic neural activity regulates neuronal recruitment in the adult avian song control system., Brenowitz E A, Perkel D J, Gale S D, Larson T A, Wang T -W, Thatra N M, and Caras M L, Proceedings of the National Academy of Sciences, Volume 110 (2013)
- Estradiol selectively enhances auditory function in avian forebrain neurons, Brenowitz E A, Caras M L, O’Brien M O, and Rubel E W 2012, Journal of Neuroscience , 2012, Volume 49 (2012)
- Seasonal Changes in Androgen Receptor mRNA in the Brain of the White-crowned Sparrow, Brenowitz E A, Fraley G S, Steiner R A, and Lent K, Gen Comp Endocrinol, 2010, Volume 166, p.66-71 (2010)
- Neuroprotective effects of testosterone in a naturally-occurring model of neurodegeneration in the adult avian song control system, Brenowitz E A and Thompson C K, Journal of Comparative Neurology, 2010, Volume in press (2010)
- Time course of changes in Gambel's white-crowned sparrow song behavior following transitions in breeding condition, Brenowitz E A, Meitzen J, Perkel D J, Thompson C K, and Choi H, Horm Behav, 2009, Volume 55, Issue 1, p.217-27 (2009)
- Plastic and stable electrophysiological properties of adult avian forebrain song-control neurons across changing breeding conditions, Brenowitz E A, Meitzen J, Weaver A L, and Perkel D J, J Neurosci, 2009, Volume 29, Issue 20, p.6558-67 (2009)
- The role of neurotrophins in the seasonal-like growth of the avian song control system, Brenowitz E A and Wissman A M, J Neurosci, 2009, Volume 29, Issue 20, p.6461-71 (2009)
- Time course of changes in Gambel's white-crowned sparrow song behavior following transitions in breeding condition, Perkel David J, Meitzen John, Thompson Christopher K, Choi Heejung, and Brenowitz Eliot A, Hormones and Behavior, 2009, Volume 55, Issue 1, p.217-227 (2009)
- Plastic and stable electrophysiological properties of adult avian forebrain song-control neurons across changing breeding conditions, Brenowitz E A, Meitzen J, Weaver A L, and Perkel D J, J Neurosci, 2009, Volume 29, Issue 20, p.6558-67 (2009)
- Neurogenesis in an adult avian song nucleus is reduced by decreasing caspase-mediated apoptosis, Brenowitz E A and Thompson C K, J Neurosci, 2009, Volume 29, Issue 14, p.4586-91 (2009)
- Caspase Inhibitor Infusion Protects an Avian Song Control Circuit from Seasonal-Like Neurodegeneration, Thompson Christopher K and Brenowitz Eliot A, J. Neurosci., 2008, Volume 28, Issue 28, p.7130-7136 (2008)
- Plasticity of the song control system in adult birds, Zeigler H P, Marler P, and Brenowitz E A, Neuroscience of birdsong, 2008, p.332-349, Cambridge, Cambridge University Press (2008)
- Steroid hormones act transsynaptically within the forebrain to regulate neuronal phenotype and song stereotypy, Brenowitz E A, Lent K, Meitzen J, Perkel D J, and Moore I T, J Neurosci, 2007, Volume 27, Issue 44, p.12045-57 (2007)
- Seasonal changes in intrinsic electrophysiological activity of song control neurons in wild song sparrows, Brenowitz E A, Meitzen J, and Perkel D J, J Comp Physiol A Neuroethol Sens Neural Behav Physiol, 2007, Volume 193, Issue 6, p.677-83 (2007)
- Seasonal-like plasticity of spontaneous firing rate in a songbird pre-motor nucleus, Brenowitz E A, Meitzen J, Perkel D J, Moore I T, and Park K H, J Neurobiol, 2005, Volume 64, Issue 2, p.181-91 (2005)
-